14 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Cytoplasmic Patterns ... Nuclear Patterns ... ARUPConsult @ARUPLabs #ANA ... #differential # ... diagnosis #rheumatology
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... similar aggregation pattern ... and platelet morphology ... agonists • This pattern ... #disorders #hematology
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Testing - Nuclear Patterns ... Homogeneous pattern ... ) Speckled pattern ... #differential # ... diagnosis #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Platelet Disorders ... - Differential ... gastric bypass), LFT ... #Disorders #Differential ... #Workup #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... / Bruising - Differential ... Platelet Function ... ASA) • Renal Disease ... #Hematology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
serial dilution, a pattern ... significant • Pattern ... : The ANA patterns ... Patterns and Associated ... #patterns #rheumatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Cryoglobulinemia (MIXED) • ANCA ... Vasculopathy #Purpura #Differential ... #Diagnosis #hematology ... #rheumatology #
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Disorders - Differential ... involvement, irregular pattern ... Lymphoproliferative #Disorders ... pathophysiology #Hematology ... Diagnosis #NonHodgkin #differential
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
Hemostasis - Differential ... Qualitative defect in platelets ... characteristic of a platelet ... discern these causes ... #Diagnosis #Hematology
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
anticoagulants • Unusual pattern ... non-accidental injury Pattern ... membrane bleeding and ... characteristic of platelet ... pediatrics #diagnosis #hematology