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hematology ana antinuclear antibody cardiology ecg electrocardiogram neurology testing antibodies cytoplasmic dermatology management nuclear pulmonary rash syndromes thrombocytopenia algorithm alopecia
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
and Cytoplasmic Patterns ... Nuclear Patterns ... • Homogeneous pattern ... #differential # ... diagnosis #rheumatology
Deep T Wave Inversions - Differential Normal variants A. Juvenile T wave pattern
Juvenile T wave pattern ... related neurogenic patterns ... Typical patterns ... to as 'strain" patterns ... #Diagnosis #Causes
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Testing - Nuclear Patterns ... Homogeneous pattern ... ) Speckled pattern ... #differential # ... diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
serial dilution, a pattern ... significant • Pattern ... : The ANA patterns ... not specific ANA Patterns ... diagnosis #differential
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential ... Diagnosis Algorithm ... methotrexate) • Drugs Autoimmune ... #Causes #Hematology
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
: Subacute • Pattern ... : Subacute • Pattern ... or subacute • Pattern ... Insidious/slow • Pattern ... #rheumatology #
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Sjogren's Syndrome (SS ... Antibodies #ANA #patterns ... #rheumatology # ... diagnosis #differential
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential ... Diagnosis Secondary ... . autoimmune, TB ... #Diagnosis #Causes
Antinuclear Antibody Testing Cytoplasmic Patterns Reticular/AMA: • PBC, SSc, PBC/SSc OS, PBC/SjS OS • AMA Speckled: •
Testing Cytoplasmic Patterns ... PBC/SSc OS, PBC/SjS ... #Cytoplasmic #Patterns ... #differential # ... diagnosis #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... Extravascular #Causes ... #differential # ... diagnosis #hematology
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