19 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
and Cytoplasmic Patterns ... Nuclear Patterns ... • Homogeneous pattern ... #differential # ... diagnosis #rheumatology
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Testing - Nuclear Patterns ... Homogeneous pattern ... ) Speckled pattern ... #differential # ... diagnosis #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
serial dilution, a pattern ... significant • Pattern ... : The ANA patterns ... not specific ANA Patterns ... Antibodies #ANA #patterns
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Sjogren's Syndrome (SS ... Antibodies #ANA #patterns ... #rheumatology # ... diagnosis #differential
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Platelet Disorders ... - Differential ... gastric bypass), LFT ... #Differential # ... #Workup #hematology
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Focal Hair Loss Pattern ... Diffuse Hair Loss Pattern ... Alopecia: - Pattern ... alopecia in men (male pattern ... loss), Female pattern
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... similar aggregation pattern ... agonists • This pattern ... #hematology #hemepath ... #differential #
Antinuclear Antibody Testing Cytoplasmic Patterns
Reticular/AMA: 
 • PBC, SSc, PBC/SSc OS, PBC/SjS OS
 • AMA
Speckled:
 •
Testing Cytoplasmic Patterns ... PBC/SSc OS, PBC/SjS ... #Cytoplasmic #Patterns ... #differential # ... diagnosis #rheumatology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... - Differential ... involvement, irregular pattern ... Lymphoproliferative #Disorders ... pathophysiology #Hematology
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
and obstructive pattern ... myeloproliferative disorders ... disease, thyroid disorders ... Classification #Diagnosis #Differential ... #Causes