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Algorithm for the Diagnosis and Workup of Hemolytic Anemia By Dr. Kylie Adamek @KylieAdamek #Hemolytic #Anemia #Algorithm #Differential
Algorithm for the ... Diagnosis and Workup ... #Anemia #Algorithm ... #Differential #Diagnosis ... #Workup #Hematology
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
- Differential Diagnosis ... Algorithm Signs ... of anemia and hemolysis ... #Differential #Diagnosis ... #Algorithm #hematology
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... #Algorithm #Differential ... Causes #Workup #Hematology ... #Diagnosis *
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... usually IgG) (e.g. lupus ... disease, Copper and ... #differential #diagnosis ... #hematology #anemia
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Algorithm • Sickle ... diverse genotypes): SS ... #Algorithm #workup ... #hematology #testing
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential Diagnosis ... Algorithm Extravascular ... #Differential #Diagnosis ... #Algorithm #Causes ... #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
- Differential Diagnosis ... Algorithm Infectious ... Inflammatory • Systemic Lupus ... Serum Sickness Hemolytic ... #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... blood loss, Acute hemolysis ... Inflammatory Conditions: Rheumatologic ... Acute bacterial and ... #Algorithm #hematology
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
microangiopathic hemolytic ... laboratory diagnosis ... Microangiopathic hemolytic ... other testing ... #anemia #Hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
- Differential Diagnosis ... Inflammatory and ... Diseases: • Systemic lupus ... Antibody-mediated hemolysis ... #Hematology
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