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diagnosis management dermatology disease hematology ana antibody antinuclear erythematosus lupus patterns sle stills vasculitis adultonset algorithm anemia blood comparison cytoplasmic
Fever and Rash - Differential Diagnosis Framework • Viral: Measles, Infectious Mono (EBV, CMV), Acute HIV,
Fever and Rash - ... Differential Diagnosis ... Noninfectious: SJS ... Medicine @SCVMCMed #Fever ... #Rash #Differential
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody Testing ... pattern: - SjS ... Antinuclear #Antibody #Testing ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
skin syndrome (SSS ... Nikolsky sign, the differential ... erythematous rash ... #Erythematous #Rash ... #Differential
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... diverse genotypes): SS ... bartonella (oroya fever ... Algorithm #workup #hematology ... #testing
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... infection Malar rash ... • Rheumatic fever ... #skin #rashes #differential ... #diagnosis #rheumatology
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
with urticarial rash ... Rash: • Nonpruritic ... 390C (102.20F) lasting ... maculopapular skin rash ... AOSD #diagnosis #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... arthritis, Skin rash ... fraction < 20% Differential ... management #treatment #rheumatology
Kawasaki Disease (KD) - Diagnosis and Management Summary Kawasaki Disease (KD) is the most common vasculitis of
Presentation: • Fever ... Diagnostic Criteria - Fever ... lasting ≥ 5 days ... Polymorphous rash ... KD #vasculitis #rheumatology
Antinuclear Antibody Testing Cytoplasmic Patterns Reticular/AMA: • PBC, SSc, PBC/SSc OS, PBC/SjS OS • AMA Speckled: •
Antinuclear Antibody Testing ... PBC/SSc OS, PBC/SjS ... Antinuclear #Antibody #Testing ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
69% - Malar rash ... 40% - Fever 36% ... (aPL) 30-45% Differential ... symptoms #mimickers #differential ... #rheumatology
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