618 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
pattern: - SjS ... Raynaud phenomenon, SjS ... PBC/SSc OS, PBC/SjS ... polar: - SLE, SjS ... differential #diagnosis #rheumatology
Antinuclear Antibody Testing Cytoplasmic Patterns
Reticular/AMA: 
 • PBC, SSc, PBC/SSc OS, PBC/SjS OS
 • AMA
Speckled:
 •
PBC/SSc OS, PBC/SjS ... Speckled: • SLE, SjS ... Neurologic conditions, SjS ... polar: • SLE, SjS ... differential #diagnosis #rheumatology
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Speckled pattern: • SjS ... Raynaud phenomenon, SjS ... differential #diagnosis #rheumatology
Stevens-Johnson syndrome (SJS), Toxic epidermal necrolysis (TEN) and Overlap

 SJS-TEN overlap and TEN - Surface Epidermal
Stevens-Johnson syndrome (SJS ... and Overlap SJS-TEN ... Distinguishing Features #SJS
Tweetorial - Stevens Johnson Syndrome (SJS)

By Dr. Steven Chen @DrStevenTChen

#StevensJohnsonSyndrome #SJS #Dermatology #Diagnosis #Tweetorial #Pathphysiology
Johnson Syndrome (SJS ... StevensJohnsonSyndrome #SJS
Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Erythematosus #SLE #hematology ... #rheumatology #
DRESS Syndrome vs SJS/TEN
DRESS
 • Latency: 2-8 weeks
 • Rash: Morbilliform
 • Mucosal involvement: 50% have
DRESS Syndrome vs SJS ... lymphocytes and eos SJS ... DRESS #Syndrome #SJS
Severe Drug Rashes - Comparison - DRESS | SJS/TEN | AGEP | Erythroderma

DRESS 
 - Onset:
Comparison - DRESS | SJS ... target lesions SJS
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Non-infectious (malignancy, rheumatologic ... causes #Platelets #hematology
Types of hypersensitivity reactions

Type I - lgE-Mediated, Within I Hour (Anaphylaxis)
Type II - IgG or IgM
to Weeks (Rash, SJS