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Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
15-30% - Anti-Sm ... (aPL) 30-45% Differential ... symptoms #mimickers #differential
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
UCTD - Smith, Sm ... Cytoplasmic #Patterns #differential
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... anti-La/SSB, anti-Sm ... #Weakness #Differential
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
UCTD • Smith, Sm ... Nuclear #Patterns #differential
Trichomonas on Urine Microscopy Trichomonas organism adjacent to WBC’s and a macrophage - brightfield with SM stain
brightfield with SM
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 Trichomonas on Urine Microscopy Trichomonas organisms adjacent to mixed cellular cast containing WBC's, tubular epithelial cells, and
brightfield with SM
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 Fernando SM et al. Prognostic Accuracy of the Quick Sequential Organ Failure Assessment for Mortality in
Fernando SM et al
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
ELISA) - Anti-Sm ... of antibody to Sm
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
Anti-dsDNA, Anti-Sm
Urine Microscopy - Urinary Sediment Examination Instructions Preparation of the urine for microscopic examination: • Clean catch
Add one drop of SM ... been stained with SM ... will displace any SM ... when used with SM
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