13 results
Diabetes Pathophysiology and Medication Targets

The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... and Medication ... used diabetes medications ... #Medication #Targets ... #Drug #Endocrinology
Antiplatelet Drugs and their Actions

- Amy Chung, MD, MSc
@AmyChung

#Antiplatelet #Medications #Pharmacology #Pathophysiology #Drugs #Agents #COX #GIIbIIIa
Antiplatelet Drugs ... #Antiplatelet #Medications ... #Pharmacology #Pathophysiology ... #Drugs #Agents
Medications causing Acute Kidney Injury (AKI)
Prerenal:
 • Dehydration: Diuretics
 • Altered intrarenal autoregulation: ACEIs / ARBs,
Medications causing ... decongestants) • Any drug ... antihistamines, TCAs, SSRIs ... Kidney #Injury #Medications ... #Drugs #pharmacology
Drugs for Heart Failure

#medications #chf #pathophysiology #cardiology #pharmacology
Drugs for Heart ... Failure #medications ... #chf #pathophysiology
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Drug-Induced Edema ... Drug-induced edema ... caused by many drugs ... DrugInduced #Edema #Medication ... #Pharmacology #Pathophysiology
Secondary causes of Hypertension
 • Medications, Drugs, Chemo: NSAIDS, Steroids, CNI, Alcohol, Cocaine, OCP, Licorice, MAOI,
Hypertension • Medications ... , Drugs, Chemo: ... Pseudopheochromocytoma - respond to SSRIs
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... differential #diagnosis #pathophysiology ... pharmacology #potassium #medications
Uric Acid Homeostasis
In the liver, purines are metabolized to uric acid. The last step in purine
The gout drug pegloticase ... Homeostasis #Gout #Pathophysiology ... #Pharmacology #Medications
Euglycemic Diabetic Ketoacidosis (EuDKA)
SGLT2 Inhibitors
Increasing Indications
Significant Adverse Drug Effects
Definition of EuDKA
 • Metabolic acidosis with pH
Inhibitors Increasing Indications ... Significant Adverse Drug ... level < 200 mg/dL Pathophysiology
Drug-Induced Urinary Retention

Drug-induced urinary retention is very common and can be caused by many classes of
Drug-Induced Urinary ... Retention Drug-induced ... many classes of medication ... blockers • SSRI/SNRI ... drugs By Dr.