10 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... workup, including BM ... Malignancy: Metastatic cancer ... Acute bacterial and ... Thrombocytosis #Platelets #Differential
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... function test, ANA ... or if a primary hematologic ... When do you do a BM ... Causes #Workup #hematology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
phenomenon, SjS, cancer ... NXP-2 (MORC3 or MJ ... ARUPConsult @ARUPLabs #ANA ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
DIAGNOSIS Labs: • BMP ... coagulopathy) • CBC w differential ... antibody, Anti-GBM ... BNP, troponin if concern ... Renal #Syndromes #differential
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
cells - Blood and ... cells - Blood & BM ... • Cytopenia -> BM ... lymphoid organs When Cancer ... #Leukemia #Hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... from germinal center ... normal germinal center ... Immunohistochemical studies (to differentiate ... classification #hematology
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
Neutropenia - Differential ... Maternal hypertension and ... replacing the BM ... replacing the BM-common ... diagnosis #causes #hematology
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
phenomenon, SjS, cancer ... NXP-2 (MORC3 or MJ ... ARUPConsult @ARUPLabs #ANA ... Nuclear #Patterns #differential ... #diagnosis #rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
acute HIV, HBV, EBV ... ovarian tumors, lung cancers ... gastric tumors • Hematology ... Gap #ProteinGap #differential ... #diagnosis #hematology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... • Anti-TIF1 (cancer-associated ... • Anti-NXP2 (ANA ... -1 antibodies (ANA ... #differential #