130 results
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
• Homogeneous: Systemic ... ) • Speckled: Systemic ... Sjogren's Syndrome (SS ... • Peripheral: Systemic ... Kumfer @AnnKumfer #Antinuclear
Systemic Autoimmune Disorders 
#RA #SS #Sjogren’s_Syndrome #Autoimmine_disorders
Systemic Autoimmune ... Disorders #RA #SS
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... • Homogeneous: Systemic ... ) • Speckled: Systemic ... Sjogren's Syndrome (SS ... Kumfer @AnnKumfer #Antinuclear
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... • MCTD (SLE/systemic ... severe disease Treatment ... @AnnKumfer #Systemic
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... 30-40% Target: SS-A ... Lupusreference #Antinuclear ... autoantibodies #Systemic
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... antibodies) • Systemic ... drug-induced SLE) • Systemic ... Jcortesizaguirr #ANA #Antinuclear
I’M DAMN SHARP - Lupus Diagnosis Mnemonic
I  	 Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid)
M 	 Malar Rash
D
Discoid Rash A Antinuclear ... IMDAMNSHARP #sle #systemic
Comparison - Serotonin Syndrome, Neuroleptic Malignant Syndrome, and Malignant Catatonia

- BWH Medicine Chiefs @BrighamChiefs

#Serotonin #Syndrome #Neuroleptic
Catatonia #NMS #SS ... diagnosis #management #treatment
Algorithm for the Diagnosis of Serotonin Syndrome
 - Serotonin syndrome is thought to be caused by
medication leading to SS ... association with SS ... extremities in SS ... initiation of treatment
Treatment of NMS
 Dopamine antagonists should be discontinued immediately in patients suspected of NMS. Like SS,
Treatment of NMS ... Like SS, the mainstay ... treatment of NMS ... Syndrome #NMS #Treatment