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Scleroderma Associated Telangiectasia.

If you see them-round, often well circumscribed (but can be matte-like too) &

CTD especially SSc ... Telangiectasia #clinical

Antinuclear antibodies and Systemic lupus
Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can

lupus (90%) Anti-SSA ... 30-40% Target: SS-A ... Sjogren Anti-SSB ... -15% If SLE is clinically ... Associated with SLE-SSc-AlM

Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
• Homogeneous pattern:
-

pattern: - SLE, SSc ... SjS, SLE, DM, SSc ... , PM/SSc OS, MCTD ... pattern: - SSc ... , PBC/SSc OS

Autoantibodies in Rheumatology
• Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and

Anti-Smith, Anti-Ro (SSA ... ) and Anti-La (SSB ... Syndrome: Anti-Ro (SSA ... ), Anti-La (SSB) ... Systemic Sclerosis, SSc

Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like

likely it will be clinically ... Sjogren's Syndrome (SS ... or scleroderma (SSc

POCUS Echocardiography - Table of Cardiac Views and Windows
• Parastemal Long-Axis View (PLAX)
• Parasternal

• Subcostal (SC ... Inferior Vena Cava (SC ... View (A5C) • SC ... Suprasternal Notch (SSN ... View (A3C) • SSN

Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3

of Scleroderma (SSc ... renal crisis (SRC ... #Scleroderma #SSc

Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern:
• SLE, SSc, AIH, JIA
• dsDNA, chromatin,

pattern: • SLE, SSc ... SjS, SLE, DM, SSc ... , PM/SSc OS, MCTD ... , PBC/SSc OS • ... , PM/SSc OS, Raynaud

ANA Patterns and Associated Rheumatic Diseases:
• Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease

Sjogren's Syndrome (SS ... or scleroderma (SSc

Management of interstitial lung disease (ILD)-associated with systemic sclerosis (SSc)

Therapeutic indication: absolute decline in FVC >10%

systemic sclerosis (SSc ... systemicsclerosis #SSc

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