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Staphylococcal Scalded Skin Syndrome (SSSS) 
(aka Ritter disease)

#Staphylococcal #Scalded #Skin #Syndrome #SSSS #Diagnosis #Pediatrics #Dermatology #Ritter
Staphylococcal Scalded ... Skin Syndrome (SSSS ... Ritter disease) #Staphylococcal ... Skin #Syndrome #SSSS
Staphylococcal Scalded Skin Syndrome (SSSS)

A 5-year-old girl presents to the ED with a rash that started
Staphylococcal Scalded ... Skin Syndrome (SSSS ... #Staphylococcal ... Skin #Syndrome #SSSS
IDSA - Antimicrobial Therapy for Staphylococcal and Streptococcal Skin and Soft Tissue Infections
 • Impetigo (Staphylococcus
Antimicrobial Therapy for Staphylococcal ... • Impetigo (Staphylococcus ... Infections #SSTIs #Staphylococcal
Staphylococcal Scalded Skin Syndrome (SSSS) 
(aka Ritter disease) 
Nikolsky positive 
Clinical 
• Typically occurs 3 to
Staphylococcal Scalded ... Skin Syndrome (SSSS ... failure) #Staphylococcal ... Skin #Syndrome #SSSS ... Staphylococcus
Common Childhood Exanthems - Differential Diagnosis
1) Rubeola (Measles) - Measles morbillivirus (MeV)
2) Scarlet Fever - Streptococcus
Rubella Virus 4) Staphylococcal ... Skin Syndrome - Staphylococcus
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
in adults and staphylococcal ... skin syndrome (SSS ... shock syndrome (TSS
Streptococcal Toxic Shock Syndrome (STSS)
Complication of invasive GAS disease characterized by shock & MOF → occurs
Shock Syndrome (STSS ... tissue necrosis STSS ... therapy in suspected STSS ... Shock #Syndrome #STSS
Transplant Infections Timeline
Pre-transplant:
 • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut)
 • Viruses: HSV (reactivation)
Engraftment:
(endogenous): Staphylococci ... Streptococci (oral), Staphylococci ... Streptococcus pneumonia, Staphylococcus
Doxycycline - Coverage and Indications
 • Staphylococci (S aureus + CoNS)
 • The tick stuff: Borrelia
Indications • Staphylococci ... , Tularemia • STIs
Endocarditis Algorithm - Infective vs Noninfective Causes
Noninfective:
 • Malignancy
 • Autoimmune disease
 • Systemic infection
Native Valve
Valve - Acute: • Staphylococcus ... streptococci • Staphylococcus ... gallolyticus • Staphylococcus ... aureus • Staphylococcus ... aureus • Staphylococcus