9 results
Cutaneous Manifestations of Monoclonal Gammopathy
 • Extravascular lg Deposits: Systemic amyloidosis, Nodular amyloidosis, Macroglobulinoderma, Follicular hyperkeratotic
Manifestations of Monoclonal ... Gammopathy • ... #gammopathy #Cutaneous ... manifestations #dermatology ... #skin #clinical
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Monoclonal Gammopathy ... of Clinical Significance ... capillary leak syndrome ... • Schnitzler syndrome ... #Gammopathy #Clinical
Suggested algorithm for follow-up of monoclonal gammopathy of undetermined significance (MGUS)
Mayo Clinic Risk Stratification Model. CBC,
for follow-up of monoclonal ... gammopathy of undetermined ... significance (MGUS) Mayo Clinic ... #monoclonal #gammopathy ... diagnosis #management #hematology
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
patients with monoclonal ... gammopathy of undetermined ... whom there are no clinical ... #monoclonal #gammopathy ... diagnosis #management #hematology
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
Gammopathy of Undetermined ... glycoprotein (MAG ... rituximab (in clinical ... #Gammopathy #Complications ... #diagnosis #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
- Idiopathic monoclonal ... Cold Agglutinin Syndrome ... Viral Infection Clinical ... gammopathy of undetermined ... hemolytic #anemia #hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Can Feature A Monoclonal ... myopathy • Anti MAG ... Amyloidosis and monoclonal ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
it represents a monoclonal ... Causes of Monoclonal ... endocrinopathy, monoclonal ... gammopathy, and ... changes (POEMS syndrome
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... Relapsing-remitting course +++ Clinical ... edema, compartment syndrome ... Monoclonal gammopathy ... Capillary #leak #syndrome