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management hematology differential gastroenterology syndrome algorithm ascites causes chronic hepatopulmonary infectiousdiseases liver aclf acute afib anticoagulant apixaban apml biliary bleed
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
those with CLD (± cirrhosis ... months without treatment ... Kidney Failure Coagulation ... #Hepatology #gastroenterology ... #management #diagnosis
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation C Congestive Heart Failure 1 H Hypertension 1 A2 Age >75 2 D Diabetes Mellitus 1 S2 Stroke,
bleed risk on anticoagulation ... Liver (cirrhosis ... Stroke #Bleed #Anticoagulation ... #AFib #Diagnosis ... #Hematology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... clot #PT #PTT #diagnosis ... #models #hematology ... #pathophysiology ... #anticoagulation
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... + Bleeding Treatment ... #diagnosis #causes ... #treatment #management ... #hematology
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
> 1.1 g/dL) 1. ... disease - Cirrhosis ... Ascites #Causes #diagnosis ... #differential #hepatology ... #SAAG
Peritonitis - Spontaneous vs Secondary vs Peritoneal Dialysis Associated Peritonitis Spontaneous Bacterial Peritonitis • Cirrhosis (high SAAG)
Peritonitis • Cirrhosis ... (high SAAG) + ascites ... fluid protein > 1 ... (at least 2): 1) ... Secondary #Peritoneal #diagnosis
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary Cirrhosis ... Female:Male 9:1 ... 65 years PBC Pathophysiology ... • AMA titer 1: ... #workup #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
- Half life: 1 ... • Albumin • Coagulation ... • Cirrhosis: > ... liver #chemistry #diagnosis ... #differential #Hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm • Who to treat: Essentially treat the pts with
Hepatitis B - Diagnosis ... viremia or have cirrhosis ... Hbe-Ag. anti-Hbe ... #Management #Treatment ... #Hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... symptoms, or> 1 ... Renal Failure Treatment ... #management #hematology
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