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diagnosis symptoms management differential erythematosus lupus sle neurology hematology autoantibodies disease sclerosis table treatment ana antibodies antinuclear arthritis autoimmune msk
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Normal CK - Myositis ... Musculoskeletal #Complications ... #pathophysiology ... #signs #symptoms
Systemic Sclerosis (Scleroderma) Limited - CREST: • Calcinosis • Raynaud phenomenon • Esophageal dysmotility • Sclerodactyly •
Systemic Sclerosis ... involve DIP • Myositis ... @AnnKumfer #Systemic ... Scleroderma #diagnosis #signs ... #symptoms #rheumatology
Ramsay Hunt Syndrome - Herpes Zoster Oticus Triad: 1. Ipsilateral facial paralysis 2. Ear pain 3. Vesicles
Ramsay Hunt Syndrome ... and auricle Complications ... neuropathy • Myelitis ... • Stroke syndromes ... Diagnosis #Symptoms #Signs
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
weakness, less systemic ... heliotrope rash, Shaw sign ... , holster sign, ... anti-synthetase syndrome ... #diagnosis #rheumatology
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
Myositis Specific ... TIF1y, NXP2, Mi-2, SAE ... Anti-Synthetase Syndrome ... Inclusion Body Myositis ... clinical #diagnosis #rheumatology
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... - Budd Chiari Syndrome ... Gastrointestinal #Complications ... #pathophysiology ... #signs #symptoms
Carcinoid Syndrome - Pathophysiology, Signs and Symptoms Symptoms: Flushing, diarrhea, palpitations, bronchospasm Complications: Carcinoid heart, mesenteric fibrosis, pellagra,
Carcinoid Syndrome ... - Pathophysiology ... , Signs and Symptoms ... bronchospasm Complications ... #Pathophysiology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Other brainstem syndromes ... pain • Extra-CNS complications ... positive NMO only): Myositis ... autoimmune disorders (Systemic ... neurology #symptoms #signs
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features of Systemic ... Demyelinating syndromes ... Glomerulonephritis Myositis ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Systemic Sclerosis ... skin thickening Signs ... acro-osteolysis, myositis ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
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