20 results
diagnosis management differential hematology neurology autoimmune disease erythematosus lupus oncology sle symptoms systemic vasculitis antibodies apml behcet calcium cerebritis chronic
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
Myositis Specific ... TIF1y, NXP2, Mi-2, SAE ... Anti-Synthetase Syndrome ... Inclusion Body Myositis ... clinical #diagnosis #rheumatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
heliotrope rash, Shaw sign ... , holster sign, ... anti-synthetase syndrome ... after 2 years of treatment ... #diagnosis #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... organ damage • Treatment ... : • Pathophysiology ... diagnosis #management #hematology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Demyelinating syndromes ... Glomerulonephritis Myositis ... erythematosus #signs ... symptoms #diagnosis #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... Puncture, EEG Treatment ... CNS #neurology #rheumatology ... diagnosis #management #treatment
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neuritis • Partial myelitis ... • Or brainstem syndromes ... • Lhermitte’s sign ... Multiple Sclerosis Treatment ... management #neurology #treatment
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis ... monophasic Pathophysiology ... of Transverse Myelitis ... • Bilateral signs ... Treatment: •
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... Renal Failure Treatment ... Differentiation #Syndrome
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome ... tests in Behcet syndrome ... Arthritis, AS Treatment ... diagnosis #management #signs ... #symptoms #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... Diagnosis: HLH signs ... • Bicytopenia Treatment ... diagnosis #management #treatment ... #hematology
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