14 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... TTP/HUS, HELLP Syndrome ... Pregnancy (AFLP) Three syndromes ... AFLP #obstetrics #hematology ... #diagnosis #table
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
TIF1y, NXP2, Mi-2, SAE ... Anti-Synthetase Syndrome ... clinical #diagnosis #rheumatology ... #table
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... Pregnancy Three syndromes ... @Bloodman #Thrombocytopenia ... Obstetrics #OBGyn #Hematology ... Diagnosis #Comparison #Table
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
Bernard-Soulier Syndrome ... receptor] • Thrombocytopenia ... Grey Platelet Syndrome ... Defects #comparison #table ... differential #diagnosis #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... infections/fevers • Thrombocytopenia ... Constitutional Syndromes ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Differentiation #Syndrome ... diagnosis #management #hematology ... #oncology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
capillary leak syndrome ... Hyperviscosity syndrome ... myopathy • Anti MAG ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Neutropenia, anemia, thrombocytopenia ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... diagnosis #workup #oncology ... #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
• Nephrotic Syndrome ... Heparin-induced thrombocytopenia ... Venous #Arterial #pathophysiology ... #hematology #differential
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... platelet count (thrombocytopenia ... IDUS) • Immune Thrombocytopenia ... #diagnosis #hematology ... #oncology