17 results
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... to MDS or acute leukemia ... Medicine @SCVMCMed #Aplastic ... #management #treatment ... #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • Aplastic ... Anemia • Toxic ... Leukemia, Tumour ... #Hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Headaches • Pale skin ... and petechiae Causes ... #management
Pustular Skin Rash - Differential Diagnosis Algorithm
Pruritic / Scaly / Erythematous lesions, usually poorly demarcated
Acneiform -
Pustular Skin Rash ... body folds with satellite ... #Pustular #SkinRash ... #dermatology #Differential ... Diagnosis #Algorithm #causes
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... old, ~10,000 new cases ... cytopenias (usually anemia ... transformation to acute leukemia ... #treatment #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Systemic and Primary Causes ... renal failure/uremia ... • Lymphoma • Leukemia ... #generalized #dermatology ... Diagnosis #Algorithm #causes
Skin Ulcers by Etiology - Differential Diagnosis Algorithm
Physical:
 • Trauma
 • Pressure
 • Radiation
Vascular:
 • Arterial
Skin Ulcers by Etiology ... • Sickle Cell Anemia ... Ulcers #ulcerative #skinrash ... #dermatology #Differential ... Diagnosis #Algorithm #causes
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... Hepatomegaly • Skin ... • Neutropenia, anemia ... Pure red cell aplasia ... workup #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... -> AML: Blast crises ... - infiltrates (anemia ... CLL -> Invade Skin ... #Hematology #Oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... just beneath the skin ... • AnemiaAplastic ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia