20 results
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Causes of Neutropenia ... • Toxins • Aplastic ... Anemia • Myelodysplasia ... deficiency: • B12 ... #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic ... Anemia • Toxic ... Leukemia, Tumour ... Megakaryopoiesis • B12 ... #Hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... to MDS or acute leukemia ... Medicine @SCVMCMed #Aplastic ... #management #treatment ... #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Headaches • Pale skin ... #hematology #diagnosis ... #management
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Deficiency • B12 ... Deficiency • Aplastic ... AnemiaAnemia ... Diagnosis #Algorithm #Causes ... #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... old, ~10,000 new cases ... cytopenias (usually anemia ... transformation to acute leukemia ... #treatment #hematology
Pustular Skin Rash - Differential Diagnosis Algorithm
Pruritic / Scaly / Erythematous lesions, usually poorly demarcated
Acneiform -
Pustular Skin Rash ... body folds with satellite ... #Pustular #SkinRash ... #dermatology #Differential ... Diagnosis #Algorithm #causes
Skin Ulcers by Etiology - Differential Diagnosis Algorithm
Physical:
 • Trauma
 • Pressure
 • Radiation
Vascular:
 • Arterial
Skin Ulcers by Etiology ... • Bleomycin Hematologic ... • Sickle Cell Anemia ... Ulcers #ulcerative #skinrash ... #dermatology #Differential
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Systemic and Primary Causes ... renal failure/uremia ... • Lymphoma • Leukemia ... #generalized #dermatology ... Diagnosis #Algorithm #causes
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... Hepatomegaly • Skin ... • Neutropenia, anemia ... Pure red cell aplasia ... workup #oncology #hematology