17 results
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet
Novel (or Direct) Oral Anti-Coagulants
 • Rivaroxaban
 • Apixaban
NOAC / DOAC Pharmacology ... #NOAC #DOAC #Pharmacology ... #Prescribing #hematology
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Anticoagulants #Medications ... #Pharmacology # ... Pathophysiology #Mechanisms #DOAC ... #Hematology
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
anticoagulation #doac ... #noac #pharmacology ... #hematology #reversal
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... @Bloodman #DOAC ... Anticoagulation #Hematology ... #Pharmacology # ... Dabigatran #Edoxaban #NOAC
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Clotmaster #VTE #DOAC ... #Loading #DVT #Pharmacology ... #Hematology
Switching Between Anticoagulants and DOACs
VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant

DOI: 10.1161/JAHA.120.017559

#Anticoagulants #DOACs #anticoagulation
Edoxaban, Betrixaban, DOAC ... anticoagulation #Switching #hematology ... #pharmacology
Isolated Neutropenia - Differential Diagnosis Algorithm
Chronic (>3 months):
 • Extrinsic: Vitamins
 • Intrinsic: Congenital, Inflammatory
Transient:
 •
Non-infectious • Medications ... Noah Rosenberg @ ... Diagnosis #Algorithm #hematology
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... not available #DOAC ... #Reversal #NOAC ... anticoagulant #hematology ... #management #pharmacology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
For most indications ... management #algorithm #pharmacology ... #treatment #medications ... decisionaid #cardiology #hematology
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Tranexamic Acid - Indications ... and Pharmacology ... Tranexamic #Acid #Indications ... #Pharmacology # ... hematology