13 results
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Anticoagulants Common Reversal ... anticoagulation #doac #noac #pharmacology ... #hematology #reversal
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Anticoagulants #Medications ... #Pharmacology # ... Mechanisms #DOAC #Hematology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
For most indications ... management #algorithm #pharmacology ... #treatment #medications ... decisionaid #cardiology #hematology
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Tranexamic Acid - Indications ... and Pharmacology ... Tranexamic #Acid #Indications ... #Pharmacology # ... hematology
Atopic Dermatitis - Topical Treatment Options 
First Line: Topical Corticosteroids 
  - High Potency: Betamethasone
After non-pharmacologic ... is the newest medication ... very different skin ... #Pharmacology # ... Dermatology #Management
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
refractory disease Skin ... lesions • Derm referral ... • Early ophtho referral ... Treatment #management #pharmacology ... #rheumatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Testing Algorithm INDICATIONS ... symptoms (eg, skin ... Differential #diagnosis #hematology
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... available #DOAC #Reversal ... anticoagulant #hematology ... #management #pharmacology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
arterial thrombosis, skin ... including flushes), reverse ... exposure (prevent skin ... Management #Treatment #Hematology
Standard Heparin Reversal: Protamine
  < 30 minutes - 1 unit/100 units of heparin
  30-60
Standard Heparin Reversal ... Bloodman #Heparin #Reversal ... #Protamine #pharmacology ... #management #hematology