15 results
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
most frequent skin ... polymorphism • Satellite ... differential #diagnosis #dermatology ... #oncology #clinical ... #skin
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Anticoagulants Common Reversal ... anticoagulation #doac #noac #pharmacology ... #hematology #reversal
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
refractory disease Skin ... lesions • Derm referral ... • Early ophtho referral ... Treatment #management #pharmacology ... #rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Syndrome) is a skin ... inflamed or blistered skin ... tissue may reveal ... Syndrome #diagnosis #dermatology ... #oncology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
#Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Watchful Waiting" →several ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
overload, PCC to reverse ... diagnosis #management #hematology ... #oncology
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... available #DOAC #Reversal ... anticoagulant #hematology ... #management #pharmacology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
arterial thrombosis, skin ... including flushes), reverse ... exposure (prevent skin ... Management #Treatment #Hematology
Standard Heparin Reversal: Protamine
  < 30 minutes - 1 unit/100 units of heparin
  30-60
Standard Heparin Reversal ... Bloodman #Heparin #Reversal ... #Protamine #pharmacology ... #management #hematology