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diagnosis dermatology differential rheumatology symptoms clinical photo lupus sle systemic erythematosus vasculitis algorithm pathophysiology autoimmune causes maculopapular manifestations neck nikolsky
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Dermatomyositis ... can present with rash ... including heliotrope rash ... , Shaw sign, holster ... sign, and Gottron's
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign
Dermatomyositis A middle-aged man describes progressive difficulty combing his hair and rising from a seated position over
Dermatomyositis ... This is a case of dermatomyositis ... 1) heliotrope rash ... , 2) shawl sign, ... AndreMansoor #Dermatomyositis
Nikolsky’s Sign - Febrile & Positive Nikolsky’s Sign: Patients in this group have the potential to
Nikolsky’s Sign ... Positive Nikolsky’s Sign ... sick (Fever + Rash ... large amounts of skin ... Derm #Nikolsky #Sign
Shawl sign poikiloderma in Dermatomyositis Poikiloderma in general is a common finding in older individuals with chronic
Shawl sign poikiloderma ... in Dermatomyositis ... along with other signs ... RashDecisionz #Shawl #sign ... #Rash #Dermatomyositis
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
redness of the skin ... the Nikolsky sign ... the Nikolsky sign ... erythematous rash ... fever or Nikolsky sign
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
LcSSc) - distal skin ... thickening Signs ... changes): skin ... acro-osteolysis, myositis ... rheumatology #diagnosis #signs
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Glomerulonephritis Myositis ... erythematosus #signs
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
Inflammatory Myopathies Dermatomyositis ... heliotrope, shawl sign ... Necrotizing Autoimmune Myositis ... Inclusion Body Myositis
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis Malar rash: • A
Combination of Skin ... Diagnosis Malar rash ... on texture of skin ... migrans: • Target sign ... dermatology #arthritis #skin
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