17 results
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... Dermatomyositis ... , Shaw sign, holster ... sign, and Gottron's ... Myositis #diagnosis #rheumatology
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
polymorphism • Satellite ... Autoimmune manifestations ... (dermatomyositis ... myelodysplastic #syndrome #differential ... dermatology #oncology #clinical
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign ... auricular papules Clinical ... #rheumatology #
Shawl sign poikiloderma in Dermatomyositis

Poikiloderma in general is a common finding in older individuals with chronic
Shawl sign poikiloderma ... along with other signs ... RashDecisionz #Shawl #sign ... #Rash #Dermatomyositis ... #Dermatology #Clinical
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
Inflammatory Myopathies Dermatomyositis ... heliotrope, shawl sign ... exclusion Necrotizing Autoimmune ... Inflammatory #Myopathies #differential ... diagnosis #comparison #rheumatology
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Dermatomyositis ... Pathogenesis and clinical ... processes occur in the skin ... -> Heliotrope Rash ... Pathophysiology #Signs
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Lymphocutaneous Sporotrichiosis Infection

Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis?
Lymphocutaneous
painless nodular rash ... trauma leads to skin ... painless, no systemic signs ... biopsy preferred Differential ... Sporotrichiosis #Infection #clinical
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
(blue-purple) rash ... chest (in a V-sign ... shoulders (in a shawl sign ... auricular papules Clinical ... diagnosis #management #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... 3rd Decade Skin ... permanent alopecia Differential ... Still disease, dermatomyositis ... rheumatologic diseases