24 results
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis
Malar rash: 
 • A
Combination of Skin ... Suggestive of: Lupus ... Suggestive of: Lupus ... on texture of skin ... migrans: • Target sign
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... • Gonococcal arthritis ... • Psoriatic arthritis ... lesions • Discoid lupus
SKIN RASHES 



Skin rashes can occur from a variety of factors, including infections, heat, allergens, immune
SKIN RASHES ... Skin rashes ... erythematous, maculopapular ... fever and systemic signs ... petechiae; #purpura; #rash
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - ... Ill-appearing, vital sign ... sulfa-drug - Skin ... #Dermatology #Rash ... #Maculopapular
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Features of Systemic Lupus ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... of hip (rare), Arthritis ... erythematosus #signs
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
• Psoriatic arthritis ... - with the skin ... Polyarthritis • Systemic Lupus ... with Systemic Lupus ... like “butterfly rash
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms
Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
SLE) - Typical Signs ... , Fever, Malar rash ... , Oral ulcers, Rash ... , Arthralgia / arthritis ... Erythematosus #SLE #Signs
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Manifestations: - Arthritis ... 69% - Malar rash ... Diagnosis and Lupus ... autoantibodies #signs
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... plugging -> Discoid Rash ... inflammation on skin ... Malar (butterfly) Rash ... pathophysiology #diagnosis #signs
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
evidence of (fatigue, rash ... , inflammatory arthritis ... 3rd Decade Skin ... Photosensitive rash ... Seizures • Strokes Skin