28 results
Maculopapular Rashes - THE ALGORITHMIC APPROACH 

The term maculopapule is a portmanteau, a combination
of macule and
Maculopapular Rashes ... febrile have a wide differential ... rashes but without signs ... have a broader differential ... Central #Peripheral #Differential
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis
Malar rash: 
 • A
Combination of Skin ... Pediatrics Patient - Differential ... Suggestive of: Lupus ... migrans: • Target sign ... #differential #
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - ... Ill-appearing, vital sign ... sulfa-drug - Skin ... #Maculopapular ... Targetoid #Algorithm #Differential
SKIN RASHES 



Skin rashes can occur from a variety of factors, including infections, heat, allergens, immune
SKIN RASHES ... Skin rashes ... erythematous, maculopapular ... fever and systemic signs ... petechiae; #purpura; #rash
Pustular Skin Rash - Differential Diagnosis Algorithm
Pruritic / Scaly / Erythematous lesions, usually poorly demarcated
Acneiform -
Pustular Skin Rash ... - Differential ... body folds with satellite ... #dermatology #Differential
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Skin Conditions ... Joint Pain Rash ... infection Malar rash ... lesions • Discoid lupus ... #rashes #differential
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... plugging -> Discoid Rash ... inflammation on skin ... Malar (butterfly) Rash ... pathophysiology #diagnosis #signs
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... 69% - Malar rash ... (aPL) 30-45% Differential ... autoantibodies #signs ... symptoms #mimickers #differential
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
Vesiculobullous Skin ... Rash - Differential ... Bullous systemic lupus ... #dermatology #Differential
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Features of Systemic Lupus ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Thrombocytopenia #Lupus ... erythematosus #signs