12 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Demyelinating syndromes ... erythematosus #signs ... #symptoms #diagnosis
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
RA) or systemic lupus ... erythematosus (SLE) Signs ... / Symptoms: - ... Xeroderma (Dry skin ... #Symptoms
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
plugging -> Discoid Rash ... inflammation on skin ... Malar (butterfly) Rash ... pathophysiology #diagnosis #signs ... #symptoms #complications
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... Episcleritis Signs ... and Symptoms: ... - Lupus - Leukemia
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
arthritis - (Reiter’s syndrome ... arthritis - with the skin ... with Systemic Lupus ... should have other symptoms ... like “butterfly rash
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
rash in association ... Symptoms: • The ... • Maculopapular ... Skin involvement ... SinaiBmoreIMRes #DRESS #Syndrome
Penicillin Allergy Pathway for Antibiotic Prescription in Patients With Penicillin Allergy
Mild Reaction - Itching, Minor rash
(not hives), Maculopapular ... mucosal involvement, skin ... Stevens-Johnson syndrome ... eosinophilia systemic symptoms ... syndrome, Hemolytic
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
evidence of (fatigue, rash ... 3rd Decade Skin ... Photosensitive rash ... Seizures • Strokes Skin ... : • Symptoms limited
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
inflammation Others: • Lupus ... mucositis - Rash ... such as systemic lupus ... Presentation - Systemic Symptoms ... purpura: strong sign
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
nodes: 13-15%, skin ... (16-32%): lupus ... : (distinct symptoms ... Diagnosis #Management #Signs ... #Symptoms