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diagnosis dermatology differential symptoms rheumatology sle algorithm arthritis causes classification common complications distribution erythematosus involvements joint management manifestations mucocutaneous oncology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... infection Malar rash ... Erythema nodosum • Sarcoidosis ... spondylitis • Sarcoidosis ... lesions • Discoid lupus
Sarcoidosis Non-caseating granulomas (Composed of T-helper & inflammatory cells) Clinical: • Disease fatal in 10% of
Sarcoidosis Non-caseating ... neuropathies • Skin ... Subcutaneous nodules, lupus ... Lymphadenopathy #Sarcoidosis ... Diagnosis #Symptoms #Signs
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis Malar rash: • A
Combination of Skin ... Suggestive of: Lupus ... Suggestive of: Lupus ... on texture of skin ... migrans: • Target sign
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... plugging -> Discoid Rash ... inflammation on skin ... Malar (butterfly) Rash ... pathophysiology #diagnosis #signs
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Thrombocytopenia #Lupus ... erythematosus #signs
Common organ involvements and symptoms in Sarcoidosis Lung 89-99% - Cough, dyspnoea, wheezing and stridor Skin 16-32% -
and symptoms in Sarcoidosis ... wheezing and stridor Skin ... 16-32% - Lupus ... and syncope #Sarcoidosis ... symptoms #diagnosis #signs
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... fatigue(→ post-sarcoidosis ... nodes: 13-15%, skin ... (16-32%): lupus ... Diagnosis #Management #Signs
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Syndrome) is a skin ... sudden onset of a rash ... - Rash: multiple ... Episcleritis Signs ... ’s syndrome - Lupus
Papulosquamous Skin Rash - Differential Diagnosis Algorithm Erythrematous or violaceous papules & plaques with overlying scale •
Papulosquamous Skin ... Rash - Differential ... Auspitz sign, Koebner's ... soles • Discoid Lupus
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Purpura, ischemic skin ... inflammation Others: • Lupus ... mucositis - Rash ... such as systemic lupus ... purpura: strong sign
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