11 results
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... appearing during the disease ... polymorphism • Satellite ... (dermatomyositis ... , SLE,...) 4
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
Cutaneous manifestations ... (blue-purple) rash ... • Erythematous rash ... severity of the disease ... anti-NXP2 Abs Lung Manifestations
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Manifestations ... response -> Subacute cutaneous ... inflammation on skin ... pathophysiology #diagnosis #signs
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Erythematosus - Diagnosis Manifestations ... 69% - Malar rash ... Drug-induced lupus, Cutaneous ... Lupusreference #SLE ... autoantibodies #signs
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... : • Acute cutaneous ... scarring • Subacute cutaneous ... , dermatomyositis ... Seizures • Strokes Skin
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
in the neck Cutaneous ... (blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... had more severe disease
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
M > F Clinical Manifestations ... vasculitis) • Cutaneous ... Oral aphthae : SLE ... • Arthritis: SLE ... diagnosis #management #signs
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... - Rash: multiple ... Most common extra cutaneous ... Episcleritis Signs ... multiforme - Dermatomyositis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
mucositis - Rash ... aphthous ulcers, cutaneous ... purpura: strong sign ... of cutaneous leukocytoclastic ... vasculitis, and SLE
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
, such as SLE, atherosclerotic ... purpura: Strong sign ... of cutaneous leukocytoclastic ... , mucositis • Rash ... (lower legs), cutaneous