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differential dermatology rheumatology symptoms sle algorithm erythematosus pathophysiology systemic vasculitis clinical dermatomyositis joint peds photo syndrome alopecia antimda5 antimda5dm antinxp2
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis Malar rash: • A
and Arthritis in Pediatrics ... - Differential Diagnosis ... migrans: • Target sign ... #differential #diagnosis ... #peds #pediatrics
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... infection Malar rash ... infection • Lyme disease ... lesions • Discoid lupus ... #differential #diagnosis
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
- Diagnosis Manifestations ... 69% - Malar rash ... auto-immune, Infectious diseases ... sclerosis, Still's disease ... autoantibodies #signs
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis
Sarcoidosis Non-caseating granulomas (Composed of T-helper & inflammatory cells) Clinical: • Disease fatal in 10% of
Clinical: • Disease ... neuropathies • Skin ... Subcutaneous nodules, lupus ... #Sarcoidosis #Diagnosis ... #Symptoms #Signs
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
- Differential Diagnosis ... arthritis - with the skin ... with Systemic Lupus ... like “butterfly rash ... #Differential #Diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
plugging -> Discoid Rash ... inflammation on skin ... Malar (butterfly) Rash ... pathophysiology #diagnosis ... #signs #symptoms
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
redness of the skin ... staphylococcal scalded skin ... includes Kawasaki disease ... erythematous rash ... #Erythematous #Rash
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
evidence of (fatigue, rash ... 3rd Decade Skin ... Differential Diagnosis ... Seizures • Strokes Skin ... Erythematosus #Diagnosis
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
stages of this disease ... Skin rash and malaise ... The signs and symptoms ... late stages of disease ... #Diagnosis #Clinical
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