84 results
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
appearing during the disease ... polymorphism • Satellite ... myelodysplastic #syndrome #differential ... #diagnosis #dermatology ... #oncology #clinical
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
Brudzinski’s Sign ... Brudzinski's sign ... While the pathophysiology ... despite severe disease ... #Meningitis #Clinical
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
redness of the skin ... the Nikolsky sign ... the Nikolsky sign ... Kawasaki disease ... fever or Nikolsky sign
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... Ill-appearing, vital sign ... sulfa-drug - Skin ... Immunocompromised #Diagnosis ... Targetoid #Algorithm #Differential
Complications of Measles: Pathogenesis and Clinical Findings
 • ADEM -> Fever, headache, neck stiffness, BBD, mental
Pathogenesis and Clinical ... Fever, headache, neck ... Complications #diagnosis ... #signs #symptoms ... #pathophysiology
Kussmaul's Sign and Friedreich's Sign on Neck Examination

A middle-aged M with unknown PMH presents with dyspnea.
Kussmaul's Sign ... and Friedreich's Sign ... Most likely diagnosis ... #Kussmauls #Sign ... #PhysicalExam #Clinical
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
Pathogenesis and Clinical ... erythematosus (SLE) Signs ... Xeroderma (Dry skin ... Sjogrens #Syndrome #Pathophysiology ... #Diagnosis #Signs
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease ... Pathophsiology ... in macrophages Diagnosis ... in GBA1 gene Clinical ... #Diagnosis #Signs
Cutaneous signs of Addison's disease may be a useful clue. Hyperpigmentation especially involves sun-exposed areas and
Cutaneous signs ... of Addison's disease ... Diagnosis is more ... patients with darker skin ... AdrenalInsufficiency #Clinical
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Graves’ Disease: ... Pathogenesis and Clinical ... the etiology Signs ... endocrinology #symptoms #signs ... #diagnosis