24 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune ... thickening Signs ... and Symptoms: ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... less systemic symptoms ... heliotrope rash, Shaw sign ... , holster sign, ... Myositis #diagnosis #rheumatology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
Autoimmune diseases ... and duration of symptoms ... angioedema Other symptoms ... Urticaria #diagnosis #rheumatology ... #comparison #table
CLINICAL MANIFESTATIONS 
OF ADRENAL INSUFFICIENCY. 

Primary and secondary adrenal insufficiency:
 - Tiredness, weakness, mental depression
- Vitiligo - Autoimmune ... nervous system symptoms ... disorders: - Pale skin ... Insufficiency #Signs ... #Symptoms #Adrenal
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Common Causes: • Autoimmune ... pseudomonas) Autoimmune ... develop another autoimmune ... Reduced libido • Signs ... patches on the skin
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
accompanies other autoimmune ... erythematosus (SLE) Signs ... / Symptoms: - ... Xeroderma (Dry skin ... #Symptoms
Differentiating Features Between Central and Peripheral Cyanosis

Mechanism - Arterial destauration
Sites - Skin, mucous membrane of oral
destauration Sites - Skin ... Sites - Only skin ... Central #Peripheral #Comparison ... #Signs #Symptoms
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Non-Hodgkin's Lymphoma - Comparison ... EBV infection, Autoimmune ... Pylori) - Autoimmune ... #NonHodgkins #comparison ... #differential #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
workup for specific symptoms ... organ-specific signs ... or symptoms (eg ... , skin or esophageal ... Differential #diagnosis #hematology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology