31 results
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
most frequent skin ... appearing during the disease ... polymorphism • Satellite ... Autoimmune manifestations ... (dermatomyositis
Cutaneous and Systemic Findings in Dermatomyositis
Cutaneous Findings:
 - Heliotrope sign and edema
 - Nail-fold changes
 -
Systemic Findings in Dermatomyositis ... Interstitial lung disease ... tract - Cardiac disease ... #Dermatomyositis ... #Diagnosis #Rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
infection • Lyme disease ... Seborrhea • Dermatomyositis ... Heliotrope • Dermatomyositis ... migrans • Lyme disease ... differential #diagnosis #rheumatology
Pyoderma Gangrenosum: Autoimmune disorder resulting in a vasculitis which causes slowly progressive 
ulceration of the skin.
Pyoderma Gangrenosum: Autoimmune ... ulceration of the skin ... number of systemic diseases ... Goldberg, M.D. - UCSD ... #Gangrenosum #UCSDH
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Autoantibodies and their Disease ... common in SLE, autoimmune ... Polymyositis / Dermatomyositis ... microsomal) - Autoimmune ... diagnosis #table #rheumatology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... Dermatomyositis ... heliotrope rash, Shaw sign ... , holster sign, ... Myositis #diagnosis #rheumatology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune ... disease characterized ... thickening Signs ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... Inverse Gottron’s sign ... ulcerations • Skin ... severity of the disease ... #rheumatology #
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... , Polymyositis/Dermatomyositis ... Disorders, Infection, Autoimmune ... Thyroid, Autoimmune ... ANA #patterns #rheumatology
MIAMI Mnemonic for Differential Diagnosis of Lymphadenopathy
Malignancies
 - Kaposi sarcoma, leukemias, lymphomas, metastases, skin neoplasms
Infections
 -
lymphomas, metastases, skin ... helminthic, Lyme disease ... toxoplasmosis Autoimmune ... disorders - Dermatomyositis ... syndrome, Still disease