18 results
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
most frequent skin ... polymorphism • Satellite ... Autoimmune manifestations ... #oncology #clinical ... #skin
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... heliotrope rash, Shaw sign ... , holster sign, ... myositis, and arthritis ... Myositis #diagnosis #rheumatology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune ... LcSSc) - distal skin ... thickening Signs ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Autoimmune → Inflammation ... noninflammatory Signs ... • Syphilis - Autoimmune ... Rheumatologic Disease ... Diagnosis #MSK #rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
of the joints (arthritis ... Episcleritis Signs ... of the joints (arthritis ... , breast CA - Hematologic ... #oncology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... of hip (rare), Arthritis ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
response to local skin ... retinal damage) • Skin ... test (this is a skin ... diagnosis #management #signs ... #symptoms #rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... infection • Autoimmune ... reticularis & skin ... arthralgia, and arthritis ... classification #rheumatology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... Inverse Gottron’s sign ... ulcerations • Skin ... • Arthralgia/arthritis ... Dermatomyositis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... disease • Non-autoimmune ... rheumatologic diseases ... deficiencies • Autoimmune ... Erythematosus #Diagnosis #Rheumatology