32 results
diagnosis differential symptoms systemic dermatology management erythematosus lupus sle sclerosis syndrome vasculitis algorithm arthritis autoantibodies classification clinical comparison dermatomyositis inflammatory
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... heliotrope rash, Shaw sign ... , holster sign, ... @AnnKumfer #Autoimmune ... #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Multi-system autoimmune ... thickening Signs ... acro-osteolysis, myositis ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Systemic Sclerosis (Scleroderma) Limited - CREST: • Calcinosis • Raynaud phenomenon • Esophageal dysmotility • Sclerodactyly •
involve DIP • Myositis ... Scleroderma #diagnosis #signs ... #symptoms #rheumatology
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Diagnosis Algorithm Signs ... Hemolysis: • Autoimmune ... Anemias (AIHAs) • Alloimmune ... Diagnosis #Algorithm #hematology
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
most frequent skin ... polymorphism • Satellite ... Autoimmune manifestations ... differential #diagnosis #dermatology ... oncology #clinical #skin
Systemic Sclerosis Associated Autoantibodies Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis Anti-centromere: Limited skin disease (~93-95%), Pulmonary
anti-Sc170): Diffuse skin ... Anti-centromere: Limited skin ... Rapid progressive skin ... Anti-PM-Sc1: Overlap myositis ... Autoantibodies #diagnosis #rheumatology
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
heliotrope, shawl sign ... exclusion Necrotizing Autoimmune ... Myositis • Onset ... Inclusion Body Myositis ... diagnosis #comparison #rheumatology
Pyoderma Gangrenosum: Autoimmune disorder resulting in a vasculitis which causes slowly progressive ulceration of the skin.
Pyoderma Gangrenosum: Autoimmune ... ulceration of the skin ... Goldberg, M.D. - UCSD ... Clinical #Photo #Dermatology ... #Gangrenosum #UCSDH
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Glomerulonephritis Myositis ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Idiopathic Inflammatory Myopathies (IIM's) RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's) • Overlap Myositis
• Overlap Myositis ... features of another autoimmune ... Inclusion body myositis ... IIMs #diagnosis #rheumatology ... #dermatology #Myopathy
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