33 results
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group

< 5%
Diagnosis, causes and management ... manifestations - Skin ... with refractory disease ... #Vasculitis #Rheumatology ... #Diagnosis #Management
Treatment of Non-hepatitis C virus Cryoglobulinemia Vasculitis - French Vasculitis Study Group

MONOCLONAL CRYOGLOBULINEMIA (TYPE 1) 
IgM
Non-hepatitis C virus Cryoglobulinemia ... MONOCLONAL CRYOGLOBULINEMIA ... /or refractory disease ... #Vasculitis #Management ... #Rheumatology #
Renal involvement in 35% of mixed cryoglobulinemia vasculitis 
Associated with : 
 • Absence of skin
in 35% of mixed cryoglobulinemia ... • Absence of skin ... #Vasculitis #Management ... #Rheumatology # ... Cryoglobulinemic
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia ... - Purpura - Skin ... • Autoimmune diseases ... reticularis & skin ... classification #rheumatology
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Involving the Skin ... Vasculitis Skin ... Urticarial/LCV) - Cryoglobulinemic ... Vasculitis: • Behcet Disease ... #dermatology #rheumatology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune disease ... thickening Signs ... interstitial lung disease ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Polyangiitis (GPA) Skin ... GPA causes disease ... vasculitis Skin ... purpura • Mixed cryoglobulinemia ... rash #diagnosis #rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
vasculitis, sepsis or cryoglobulinemia ... Calciphylaxis • Cryoglobulinemia ... Warfarin-induced skin ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... Arthralgia/arthritis, Skin ... autoinflammatory diseases ... #diagnosis #management ... #treatment #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Purpura, ischemic skin ... ANCA +MPO) • Cryoglobulinemic ... purpura: strong sign ... Low levels mixed cryoglobulinemia ... differential #diagnosis #rheumatology