14 results
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
Care TRICC - NEJM ... - ICU FOCUS - NEJM ... Villaneueva - NEJM ... UGIB TRISS - NEJM ... #Thresholds #Hematology
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Treatment of Thrombotic ... HUS) Treatment ... Contraindication to platelets transfusion ... #rheumatology # ... hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
TRALI vs TACO - Transfusion ... plasma volume transfusion ... : 33% • Treatment ... : No • Treatment ... #Reactions #hematology
Thromboelastography (TEG) based therapy and Management

If r time prolonged -> FFP
If MA low -> plts/cryoprecipitate (if
50 - > platelet transfusions ... Management #Diagnosis #Hematology ... Thromboelastogram #Treatment
Thromboelastography (TEG) Based Management
 - If R time prolonged -> FFP 
 - If MA low
50 -> platelet transfusions ... TEG #Management #treatment ... #diagnosis #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Transfusion Thresholds ... maculopapular rash ... - Transfusion ... diagnosis #management #hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
megaloblastic anemia Treatment ... Supportive care (transfusions ... diagnosis #management #treatment ... #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... Non-Hemolytic Transfusion ... maculopapular rash ... • Transfusion ... diagnosis #management #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Diuretics, PRBC transfusion ... organ damage • Treatment ... Low calcium • Treatment ... - Hyperkalemia treatment ... diagnosis #management #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
incompatible blood transfusion ... + Bleeding Treatment ... hydration • RBC transfusion ... diagnosis #causes #treatment ... #management #hematology