18 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... lesions • Discoid lupus ... #dermatology #joint ... #differential # ... diagnosis #rheumatology
Inflammatory Joint Pain - Differential Diagnosis Algorithm 
Monoarticular
 • Gout (Podagra, Tophi)
 • Pseudogout
 • Early
Inflammatory Joint ... Pain - Differential ... Arthritis • Systemic Lupus ... ) Syndrome • Scleroderma ... JointPain #MSK #Differential
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... systemic sclerosis/scleroderma ... Sclerosis (scleroderma ... ANA #patterns #rheumatology ... #diagnosis #differential
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
lesions Abdominal pain ... (20%) Renal disease ... ) Blood (75%): Anemia ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... spondyloarthropathies, lupus ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup #differential
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
- Hemolytic anemia ... (aPL) 30-45% Differential ... sclerosis, Still's disease ... autoantibodies #signs ... #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pain Eyes ... Telangiectasia • Scleroderma ... Thickened skin • Scleroderma ... #pain #differential ... #diagnosis #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... noninflammatory Signs ... - Autoimmune Rheumatologic ... #pain #Differential ... Diagnosis #MSK #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Arthritis: • Joint ... pain • Swan neck ... arthropathy • 90% joints ... lymphopenia, low PLT • Anemia
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
inflammation Others: • Lupus ... vesicular eruption - Joints ... such as systemic lupus ... purpura: strong sign ... #diagnosis #rheumatology