120 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
used to detect ANAs ... • +ANA can be seen ... The higher the ANA ... : The ANA patterns ... Patterns and Associated
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
: - SLE, SSc ... : - SjS, SLE, ... Speckled: - SLE ... conditions, SjS, SLE ... ARUPConsult @ARUPLabs #ANA
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... erythematosus (SLE ... erythematosus (SLE ... Antinuclear #Antibodies #ANA ... #patterns #rheumatology
An Approach to Jaundice Workup Algorithm by CBC and LFT Pattern

- Dr. Eric Strong @DrEricStrong

#Jaundice #Workup
Workup Algorithm ... by CBC and LFT ... Pattern - Dr. ... Jaundice #Workup #Algorithm ... #Patterns #LFTs
Lab patterns seen in Inborn Errors of Metabolism

A table of lab values compiled from UpToDate and
Lab patterns seen ... from UpToDate and ... See IEM schema for ... metabolicemergency-pathophysiology-differential-pediatrics-metabolism-algorithm-diagnosis ... IEM #Laboratory #Patterns
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
) antibody • ANAs ... have ANAs; thus ... , a negative ANA ... B serology • ANAs ... multiple myeloma) • ANA
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
searched for when ANA ... Association with both SLE ... Anti-Ribo-P 5-15% If SLE ... higly specific for SLE ... rheumatology #table #ANA
Algorithm for nodular pattern
The algorithm to distinguish perilymphatic, random and centrilobular nodules is the following:
- Look
Algorithm for nodular ... pattern The algorithm ... often easiest to see ... are visible, the pattern ... #Differential #Algorithm
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Disease Associations ANA ... Non-specific; common in SLE ... RA Anti-dsDNA - SLE ... - Drug-induced SLE ... Diffuse) Anti-Sm - SLE
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
: • SLE, SSc, ... : • SjS, SLE, DM ... Ro60), SSB (La), RNA ... • Fibrillarin, RNA ... ARUPConsult @ARUPLabs #ANA