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management differential pathophysiology causes systemic vasculitis nephrology complications disease encephalopathy erythematosus hematology infarction lupus oncology psychiatry sclerosis sle treatment workup
Systemic Sclerosis (Scleroderma) Limited - CREST: • Calcinosis • Raynaud phenomenon • Esophageal dysmotility • Sclerodactyly •
Systemic Sclerosis (Scleroderma ... 10% - 15% • Scleroderma ... renal crisis ... #diagnosis #signs ... #symptoms #rheumatology
Hypertension and Altered Mental Status (AMS) - Differential Diagnosis Framework Hypertension: • Hypertensive emergency • Hypertensive encephalopathy
Pre-Eclampsia Renal ... Acute/Chronic renal ... failure • Renal ... Polyarteritis nodosa • Scleroderma ... renal crises
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
and Symptoms: ... arterial HTN) • Renal ... : scleroderma renal ... #SSc #rheumatology ... #diagnosis #signs
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... Trousseau's • Malignant hypertension ... • Scleroderma ... renal crisis • ... #hematology #hemolysis
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
Pulmonary Renal ... Complement Levels: Scleroderma ... Renal Crisis, IgA ... disease, Malignant hypertension ... AnnKumfer #Pulmonary #Renal
Cirrhosis - Illustrated signs and symptoms: Integumentary, neurologic, gastrointestinal, portal hypertension effects, hematologic, renal, metabolic, cardiovascular, reproductive #Diagnosis
- Illustrated signs ... and symptoms: ... gastrointestinal, portal hypertension ... , hematologic, renal ... #Cirrhosis #Signs
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
and Differential Diagnosis ... eg, presence of renal ... bruit or signs ... • Vascular: Renal ... Renal parenchymal
Signs and Symptoms of Renal Infarction • Abdominal or flank pain • Leukocytosis • Fever •
Signs and Symptoms ... of Renal Infarction ... defects on enhanced renal ... imaging #Renal ... #Symptoms #diagnosis
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Systemic sclerosis (scleroderma ... cases • Sjögren syndrome ... polyangiitis without renal ... ANCA+ 30-60% • Renal-limited ... #rheumatology #
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Demyelinating syndromes ... Abdominal pain (20%) Renal ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
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