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diagnosis causes intravascular thrombocytopenia algorithm anemia arterial atlas coagulation comparison dic disseminated embolism evaluation hemolytic hemolyticuremicsyndrome key management microangiopathies morphology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
: Thrombotic thrombocytopenic ... purpura (TTP), ... syndrome (HUS) ... #Causes #differential ... #diagnosis #hematology
Thrombotic Microangiopathy - TTP VS HUS Big picture points : Often hard to differentiate the two entities,
Thrombotic Microangiopathy ... - TTP VS HUS ... Often hard to differentiate ... #purpura #TTP # ... #Hematology
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table • Thrombotic Thrombocytopenic Purpura (TTP)
Microangiopathy ... Diagnosis Table ... Thrombocytopenic ... Purpura (TTP) ... #TMA #hematology
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. TTP/HUS indicates thrombotic
TTP/HUS indicates ... thrombotic thrombocytopenic ... purpura/hemolytic ... uremic syndrome ... , Hematology 2012
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
: • Thrombotic ... microangiopathies (TMA) - TTP ... syndrome (ST-HUS ... microangiopathy ... #diagnosis #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... disease - DIC/TTP ... /HUS - Hemolytic ... Diagnosis #hematology ... #nonpalpable #dermatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... Petechiae • Purpura ... DDX: • TMA’s (HUS ... /TTP/DITMA) - ... treatment #management #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
Evaluation for Thrombotic ... Thrombocytopenic ... Purpura Activity ... WBC count and differential ... Diagnosis #Workup #Hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
, Thrombotic idiopathic ... thrombocytopenia ... (ITP), Disseminated ... key #diagnosis #differential ... #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Hyperviscosity, TTP ... • Nephrotic Syndrome ... Heparin-induced thrombocytopenia ... other causes of purpura ... #hematology #differential
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