11 results
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... of schistocytes ... : • Thrombotic ... syndrome (ST-HUS ... diagnosis #hematology
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Microangiopathy (TMA) - Differential ... Diagnosis Table ... Thrombocytopenic Purpura ... Microangiopathy #TMA #hematology ... #differential #
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Often hard to differentiate ... HUGE treatment implications ... thrombocytopenic #purpura ... Comparison #Diagnosis #Table ... #Hematology
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
TTP/HUS indicates ... thrombotic thrombocytopenic ... purpura/hemolytic ... uremic syndrome ... thrombocytopenia, Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
thrombocytopenic purpura ... uremic syndrome ... (HUS) • Other ... Extravascular #Causes #differential ... #diagnosis #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - Hemolytic ... : • DIC, TTP/HUS ... Diagnosis #hematology ... #nonpalpable #dermatology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Pregnancy - TTP/HUS ... defects. 1) HELLP (Hemolysis ... * High LDH, schistocytes ... AFLP #obstetrics #hematology ... #diagnosis #table
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... Pulmonary emboli • Schistocytes ... syndrome, Thrombotic ... key #diagnosis #differential ... #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
Evaluation for Thrombotic ... Thrombocytopenic Purpura ... smear - Shows schistocytes ... WBC count and differential ... Diagnosis #Workup #Hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Petechiae • Purpura ... DDX: • TMA’s (HUS ... - MAHA: TTP/HUS ... treatment #management #hematology