34 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... Hyperkalemia ... • Increased EC shift ... differential #diagnosis #pathophysiology ... #pharmacology #
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... Transcellular Shift ... Refeeding Syndrome #Hypokalemia ... Diagnosis #Algorithm #causes ... potassium #low #pathophysiology
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
Drugs associated ... with hypokalemia ... hypomagnesemia Hypokalemia ... - Shift from extracellular ... diagnosis #nephrology #Causes
Causes of Hypokalemia

Hypokalemia results from abnormal losses, transcellular shifts, or insufficient intake (Table 1).6–8 Abnormal losses
Causes of Hypokalemia ... transcellular shifts ... insufficient intake (Table ... rarely the sole cause ... #Differential #Causes
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Drugs that Impair ... happypillsrx/ #Hyperkalemia ... #Pathophysiology ... #Pharmacology #
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Drug-Induced Edema ... is caused by many ... Edema #Medication #Causes ... #Differential #Pharmacology ... #Pathophysiology
Classification, Differential Diagnosis, and Features of Hyponatremia According to Volume Status 

Hypervolemic hypernatremia 
 - CHF
Glucocorticoid deficit - Hypokalemia ... - Drugs - ... Differential #Diagnosis #Table ... #Causes
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... reactions Common Drugs ... Causing Hyperkalemia ... Intracellular Shift ... differential #diagnosis #causes
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Drugs (Statins), ... Dermatomyositis) AKI - Pathophysiology ... Shift of extracellular ... Dialysis for severe hyperkalemia ... Management #Summary #causes
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... constipation, diarrhea, nausea ... ); nausea, vomiting ... #medications #pharmacology ... #table #comparison