12 results
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... intracellular calcium causes ... - Hyperkalemia ( ... #Pharmacology # ... Pathophysiology #cardiology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... : • Digoxin ... Intracellular Shift ... differential #diagnosis #causes ... potassium #high #nephrology
Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm
Transcellular Shift - Appropriate renal excretion (GFR,
Causes of Hyperkalemia ... Intercellular Shift ... Transcellular Shift ... -1 agonism • Digoxin ... IntercellularShift #Nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... : • Digoxin ... Intracellular Shift ... differential #diagnosis #causes ... potassium #high #nephrology
Bradycardia - Differential Diagnosis Framework

BRADI Mnemonic
 • BRASH/Hyperkalemia
 • Reduced oxygen/Glucose/Temp
 • ACS
 • Drugs
 •
channel blockers • Digoxin ... Chagas disease • Acute ... Spondylarthropathies Other causes ... differential #diagnosis #causes ... #cardiology #BRADI
Acute Atrial Fibrillation - Initial Options for Rate Control
Diltiazem IV
 •  Rapid onset and rapidly
IV bolus can cause ... long-term oral use Digoxin ... • Does not cause ... Rate #Control #pharmacology ... #management #cardiology
Cardiorenal Syndrome (CRS) Types
 • Type 1 - Acute CRS: Alteration of renal perfusion is the
Types • Type 1 - Acute ... hemodialysis and fluids shifts ... may be in cause ... Syndrome #CRS #Types #cardiology ... #nephrology
Causes of Hyperkalemia
l. Pseudohyperkalemia
  A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis
  B.
Causes of Hyperkalemia ... extracellular shift ... Digoxin and related ... High #Potassium #Classification ... #Causes
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products
Angiotensin-Converting Enzyme Inhibitors (ACEIs)
 • Night-blooming
vera, Licorice - Causes ... hypokalemia, increasing ... risk of digoxin ... supplementals #herbal #pharmacology ... #DDI #table #cardiology
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
states such as acute ... Is Dangerous in Hyperkalemia ... transcellular shift ... • Saline Causes ... NS #comparison #pharmacology