38 results
Causes of Hyperkalemia

Hyperkalemia is caused by excess potassium intake, impaired potassium excretion, or transcellular shifts. The
Causes of Hyperkalemia ... is caused by excess ... potassium intake ... , impaired potassium ... transcellular shifts
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Synthesis of aldosterone ... • Increased EC shift ... pathophysiology #pharmacology ... #potassium #medications
Causes of Hyperkalemia - Differential Diagnosis Algorithm
 • Increased Intake
 • Reduced Excretion (IV potassium with
Causes of Hyperkalemia ... Excretion (IV potassium ... Transcellular Shift ... #Hyperkalemia ... Diagnosis #Algorithm #Causes
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
that Impair Renal Potassium ... , K-ATPase and Aldosterone ... happypillsrx/ #Hyperkalemia ... Pathophysiology #Pharmacology ... #Impaired #Potassium
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS)

This is a very common pathway that clinicians should
Renin-Angiotensin-Aldosterone ... sodium, which causes ... inhibiting drug classes ... avoid harmful hyperkalemia ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... Transcellular Shift ... Refeeding Syndrome #Hypokalemia ... Diagnosis #Algorithm #causes ... #potassium #low
Causes of Hyperkalemia
Pseudohyperkalemia
 - Tourniquet use
 - Hemolysis (in vitro)
 - Leukocytosis
 - Thrombocytosis
Intra- to extracellular
Causes of Hyperkalemia ... shift - Acidosis ... intoxication - Hyperkalemic ... tacrolimus - Aldosterone ... #Causes #diagnosis
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
treated with IV potassium ... wasting from other causes ... suggests extra-renal causes ... - ↑ Renin ↑ Aldosterone ... #differential #potassium
Antiarrhythmic Drugs

CLASS IA
 • Procainamide, Quinidine, Disopyramide
CLASS 1B
 • Lidocaine, Mexiletine
CLASS 2
 • Propranolol, Esmolol
CLASS 4
Adenosine, Magnesium, Potassium ... #Medications #Classes ... #Classification ... #Pharmacology # ... cardiology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... • HTN, High Aldosterone ... @priti899 #Hypokalemia ... Diagnosis #Algorithm #causes ... #potassium #low