21 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... shift of K (Succinylcholine ... MunerMohamed1 #hyperkalemia ... #differential #diagnosis ... #pathophysiology
Causes of Hypercalcemia
Parathyroid hormone–dependent
Primary hyperparathyroidism
Familial hypocalciuric hypercalcemia
Lithium-associated
Tertiary hyperparathyroidism
Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
Causes of Hypercalcemia ... hypocalciuric hypercalcemia ... Jansen disease #Hypercalcemia ... #Differential #Diagnosis ... #Endocrinology
BRASH Syndrome

B - Bradycardia
R - Renal failure
A - AV nodal blockade
S - Shock
H - Hyperkalemia

Typical ECG
S - Shock H - Hyperkalemia ... Typical ECG ... other findings of hyperkalemia ... Aggressive treatment of hyperkalemia ... #pathophysiology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... Transcellular Shift ... - Refeeding Syndrome ... causes #potassium #low ... #pathophysiology
Causes of Hypercalcemia due to increased Vitamin D levels
 • The BIG 3:
Causes of Hypercalcemia ... Genetic: Williams syndrome ... jamiekwillows #Hypercalcemia ... #differential #diagnosis ... #endocrinology
Hypocalcemia - Differential Diagnosis Algorithm - Low and High PTH
LOW PTH - Hypoparathyroid
 - Congenital (Pediatric)
Hypocalcemia - Differential ... Diagnosis Algorithm ... Tumor lysis syndrome ... #Differential #Diagnosis ... Algorithm #PTH #endocrinology
Hypocalcemia - Differential Diagnosis Algorithm - Low and High Phosphate
LOW PHOSPHATE
 - Low/NormaI PTH
Hypocalcemia - Differential ... Diagnosis Algorithm ... Phenytoin, Nephrotic Syndrome ... #Differential #Diagnosis ... Algorithm #Phosphate #endocrinology
Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm
Transcellular Shift - Appropriate renal excretion (GFR,
Causes of Hyperkalemia ... , TTKG, distal flow ... • Cell Lysis (e.g ... Tumor Lysis Syndrome ... • Digoxin #Hyperkalemia
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
WBC >100k, + lab signs ... , Elevated Cr, Low ... hydration - Hyperkalemia ... unless worrisome EKG ... #TLS #diagnosis
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
weight loss - Low ... disturbances: low ... Metabolic Acidosis • Shift ... #diagnosis #pathophysiology ... #symptoms #signs