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differential management causes algorithm nephrology workup potassium treatment anemia rheumatology cardiology hypokalemia syndrome checklist anesthesia anesthesiology classification dermatology hepatology intraoperative
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC ... shift of K (Succinylcholine ... Benyzlpenicillin, blood ... #differential #diagnosis ... #pathophysiology
Hyperkalemia Differential Diagnosis Algorithm R/O Pseudo-hyperkalemia: • Possible Lab error! Alwavs Repeat Blood sample! • Leukocytosis, Thrombocytosis:
Diagnosis Algorithm ... Alwavs Repeat Blood ... while drawing blood ... TTKG should be high ... #pathophysiology
Emergency Management of Hyperkalemia in Adults Assess Patient - Airway Breathing Circulation Disability Exposure (ABCDE) Approach •
Management of Hyperkalemia ... clinical scenario, ECG ... Gluconate IV Shift ... Monitor K+ and Blood ... Monitor serum K+ and blood
Causes of Hypokalemia - Differential Diagnosis Algorithm Increased Loss - Increased GI Loss - Increased Urinary
Causes of Hypokalemia ... - Differential Diagnosis ... Transcellular Shift ... #Differential #Diagnosis ... potassium #low #pathophysiology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Diagnosis Framework ... phlebotomy High ... Crush injury • Blood ... Intracellular Shift ... Blood transfusion
Diagnosis of Hypokalemia - Differential Algorithm Categorized by Causes: Redistribution, Extrarenal Losses, Renal Losses (High and
Diagnosis of Hypokalemia ... Renal Losses (High ... and Low Blood Pressure ... ) #Diagnosis # ... Hypokalemia #Differential
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Diagnosis Framework ... phlebotomy High ... Crush injury • Blood ... Intracellular Shift ... Blood transfusion
Hyperkalemia - Management Algorithm • IV calcium • IV insulin and glucose and/or salbutamolt • Consider
Hyperkalemia - Management ... potassium and ECG ... blocks, QRS axis shift ... #potassium #high ... #diagnosis #management
Oxyhemoglobin Dissociation Curve Left Shift - decreased unloading of O2 at tissue level (i.e. increased
Curve Left Shift ... • stored red blood ... Dissociation #Curve #Pathophysiology ... #Left #Right #Shift ... Differential #Causes #Diagnosis
Hyperkalemia: Diagnostic algorithm Decreased renal potassium excretion • Acute renal failure • Chronic renal failure • Drugs Increased
Hyperkalemia: Diagnostic ... Potassium-rich diet • Blood ... Normal, Renin High ... hypoplasia Aldosterone high ... #Diagnosis #algorithm
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