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management syndrome differential hepatology nephrology workup alkaline alp apml bandemia blood causes cbc cell cerebritis cns crisis differentiation disorders erythematosus
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... Lumbar Puncture, EEG ... Induction Rx: high-dose ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and high ... hydration - Hyperkalemia ... unless worrisome EKG ... Syndrome #TLS #diagnosis ... #management #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... function test, ANA (e.g ... (CVID, WAS), (neurologic ... psychiatric changes), high ... Causes #Workup #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... • Attempt if high ... opacities • Diagnosis ... #management #hematology ... #oncology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Left Shift: • ... Metamyelocyte (Left Shift ... with moderate and high ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
fractures of feet, thigh ... collection with EDTA Pathophysiology ... respiratory failure • Neurologic ... Hyperlipidemia - Hypercalcemia ... Hyophosphatasia #hepatology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... High mortality. ... Hypocalcemia, Hyperkalemia ... #Transfusions #diagnosis ... #management #hematology
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
anemia (MAHA) Pathophysiology ... Biopsy to confirm diagnosis ... (short-acting, e.g ... Renal #Crisis #rheumatology ... #nephrology #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Lymphohistiocytosis (HLH) High ... is a critical diagnostic ... - Persistent high ... Pathophysiology ... #Management #Hematology
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
Pathophysiology: ... liver insult (e.g ... Prognosis: • High ... Hepatorenal #Syndrome #Hepatology ... #Nephrology #Diagnosis
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