8 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
fractures of feet, thigh ... collection with EDTA Pathophysiology ... respiratory failure • Neurologic ... Hyperlipidemia - Hypercalcemia ... Hyophosphatasia #hepatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and high ... WBC >100k, + lab signs ... hydration - Hyperkalemia ... Syndrome #TLS #diagnosis ... #management #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... Lumbar Puncture, EEG ... Induction Rx: high-dose ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Pseudohyperkalemia vs Reverse Hyperkalemia

Pseudohyperkalemia and reverse pseudohyperkalemia are both conditions where potassium levels appear falsely elevated.

Pseudohyperkalemia:
This
• No clinical signs ... potassium • ECG ... no changes in ECG ... #Potassium #Nephrology ... #Diagnosis
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Epidemiology 1) High ... survival is 93-95% Pathophysiology ... hyperphosphatemia, hypercalcemia ... (e.g. incidental ... #Management #Signs
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Lymphohistiocytosis (HLH) High ... Presentation • Common Signs ... - Persistent high ... Pathophysiology ... #Management #Hematology
Bulimia Nervosa: Complications
GASTROINTESTINAL
 • Dehydration & inability to digest food -> Constipation
 • Recurrent vomiting exposes
Binging on foods high ... of nutrients (e.g ... ) • Overall: hypokalemia ... Complications #pathophysiology ... #diagnosis #signs
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Pathophysiology: ... liver insult (e.g ... Prognosis: • High ... Hepatorenal #Syndrome #Hepatology ... #Nephrology #Diagnosis