13 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC ... shift of K (Succinylcholine ... differential #diagnosis #pathophysiology ... #pharmacology #potassium ... #medications #druginduced
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Intracellular Shift ... Medications 2. ... differential #diagnosis #causes ... #potassium #high ... #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Intracellular Shift ... Medications 2. ... differential #diagnosis #causes ... #potassium #high ... #nephrology
Causes of Hyperkalemia - Differential Diagnosis Framework
 • Cellular Shift:
   - Exercise
Causes of Hyperkalemia ... Framework • Cellular Shift ... hyperosmolality - Medications ... Differential #Diagnosis #Causes ... #potassium #high
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
- Shift from extracellular ... - Insulin (high ... hypomagnesemia #Medications ... differential #diagnosis #nephrology ... #Causes #hypomg
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
family history - Medications ... function test, ANA (e.g ... (CVID, WAS), (neurologic ... psychiatric changes), high ... #Workup #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and high ... WBC count cause ... hydration - Hyperkalemia ... unless worrisome EKG ... diagnosis #management #hematology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... heparinized tube) • ECG ... only if no clear cause ... Management #Treatment #potassium ... #nephrology #K
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... Induction Rx: high-dose ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
fractures of feet, thigh ... collection with EDTA Pathophysiology ... respiratory failure • Neurologic ... Hyperlipidemia - Hypercalcemia ... Phosphatase: • Other causes